| Issue |
EPJ Web Conf.
Volume 335, 2025
EOS Annual Meeting (EOSAM 2025)
|
|
|---|---|---|
| Article Number | 04009 | |
| Number of page(s) | 2 | |
| Section | Topical Meeting - BioPhotonics and Biosensors | |
| DOI | https://doi.org/10.1051/epjconf/202533504009 | |
| Published online | 22 September 2025 | |
https://doi.org/10.1051/epjconf/202533504009
LPG-based optical fibre sensor for the detection of the binding protein FKBP12
1 Institute of Applied Physics, National Research Council, 50019 Sesto Fiorentino, FI, Italy
2 Department of Chemistry, Univ.Florence, 50019 Sesto Fiorentino, FI, Italy
Published online: 22 September 2025
Abstract
An optical fibre sensor with a long period grating (LPG) is described for the binding protein FKBP12 detection. An ad-hoc synthesized recognition element is immobilised on the fibre surface in correspondence of the LPG by using a home-made microfluidic flow-cell. Measurement is performed by flowing solutions in the flow-cell with increasing FKBP12 concentration and measuring the shift of the LPG resonant peak.
© The Authors, published by EDP Sciences, 2025
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