EPJ Web Conf.
Volume 137, 2017XIIth Quark Confinement and the Hadron Spectrum
|Number of page(s)||8|
|Section||Section A Focus Subsection: Emergent gauge fields and chiral fermions|
|Published online||22 March 2017|
Gauge symmetries and structure of proteins
1 Laboratory of Physics of Living Matter, Far Eastern Federal University, 690950, Sukhanova 8, Vladivostok
2 Department of Physics and Astronomy, Uppsala University, P. O. Box 803, S-75108, Uppsala, Sweden
3 Laboratoire de Mathematiques et Physique Theorique CNRS UMR 6083, Fédération Denis Poisson, Université de Tours, Parc de Grandmont, F37200, Tours, France
4 Department of Physics, Beijing Institute of Technology, Haidian District, Beijing 100081, People’s Republic of China
a e-mail: firstname.lastname@example.org
Published online: 22 March 2017
We discuss the gauge field theory approach to protein structure study, which allows a natural way to introduce collective degrees of freedom and nonlinear topological structures. Local symmetry of proteins and its breaking in the medium is considered, what allows to derive Abelian Higgs model of protein backbone, correct folding of which is defined by gauge symmetry breaking due hydrophobic forces. Within this model structure of protein backbone is defined by superposition of one-dimensional topological solitons (kinks), what allows to reproduce the three-dimensional structure of the protein backbone with precision up to 1A and to predict its dynamics.
© The Authors, published by EDP Sciences, 2017
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