| Issue |
EPJ Web Conf.
Volume 309, 2024
EOS Annual Meeting (EOSAM 2024)
|
|
|---|---|---|
| Article Number | 04014 | |
| Number of page(s) | 2 | |
| Section | Topical Meeting (TOM) 4- BioPhotonics and Biosensors | |
| DOI | https://doi.org/10.1051/epjconf/202430904014 | |
| Published online | 31 October 2024 | |
https://doi.org/10.1051/epjconf/202430904014
Microbubble resonators for photoacoustic and photothermal characterisation of nanoparticles suspensions
1 CNR-IFAC Istituto di Fisica Applicata Nello Carrara, Consiglio Nazionale delle Ricerche, Via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy
2 Universidad Autónoma de la Ciudad de México, Prolongación San Isidro 151, Colonia San Lorenzo Tezonco, Ciudad de México C.P. 09790, Mexico
* e-mail: g.frigenti@ifac.cnr.it
Published online: 31 October 2024
We discuss the implementation of Whispering Gallery Modes Microbubble resonators (MBRs) as unique platforms for photoacoustic (PA) detection and photothermal (PT) spectroscopy. In a first experiment, the MBR transducer allowed to detect the PA signal generated by a suspension of gold nanorods (GNRs) within its core, leveraging on the MBR sharp optical spectrum and high sensitivity towards mechanical perturbations. Both static and flow-cytometry configuration were tested, finding that the MBR mechanical modes help detection by decoupling the environmental noise from the PA oscillation. In a second experiment, the MBR transducer allowed to reconstruct the GNRs absorption spectrum through the photothermal (PT) conversion, leveraging on high sensitivity towards temperature variations. We verified the scattering-free nature of the detection by using milk-stained GNRs suspension. We also found that the active locking of the MBR resonance increases the system sensitivity by an order-of-magnitude. These results make MBRs interesting candidates for combined PA and PT characterisation of extremely small samples for medical diagnosis, quality controls in food safety and chemical production processes.
© The Authors, published by EDP Sciences, 2024
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