| Issue |
EPJ Web Conf.
Volume 348, 2026
3rd International Conference on Innovations in Molecular Structure & Instrumental Approaches (ICMSI 2026)
|
|
|---|---|---|
| Article Number | 02001 | |
| Number of page(s) | 22 | |
| Section | Chemistry | |
| DOI | https://doi.org/10.1051/epjconf/202634802001 | |
| Published online | 21 January 2026 | |
https://doi.org/10.1051/epjconf/202634802001
Advancements in the Bio-efficacy of Gold-based Complexes: A Comprehensive Review of Synthetic Approach and Therapeutic Potential
1 BRCC Laboratory, Department of Chemistry, School of Science, RK University, Rajkot 360020, Gujarat - India
2 Department of Microbiology, Shri O. R. Bhalodia Mahila Science College, Affiliated to Saurashtra University, Tankara 363650, Gujarat - India
* E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Published online: 21 January 2026
Gold-based compounds have emerged as promising candidates in medicinal chemistry due to their unique physicochemical properties and broad therapeutic potential. This review highlights recent developments in gold (I), gold (III), and gold-nanomaterial systems, emphasizing their anticancer, anti-inflammatory, antimicrobial, antiviral, and neuroprotective activities. Key mechanisms include redox modulation, enzyme inhibition, and targeted biomolecular interactions. Advances in gold-polymer composites and nanoscale architectures have improved stability, selectivity, and controlled drug release, expanding their relevance in precision medicine. Clinically progressing platforms such as gold nanocrystals, nanoshell photothermal agents, and nucleic-acid-functionalized constructs underscore their translational promise. Additionally, diverse synthetic strategies and structure-activity insights demonstrate the advantages of gold over other metals. Conclusively, this review outlines gold's growing impact on therapeutic innovation and biomedical research.
© The Authors, published by EDP Sciences, 2026
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