Open Access
Issue
EPJ Web Conf.
Volume 340, 2025
Powders & Grains 2025 – 10th International Conference on Micromechanics on Granular Media
Article Number 11003
Number of page(s) 4
Section Powders and Grains in Pharma- and Food Processes
DOI https://doi.org/10.1051/epjconf/202534011003
Published online 01 December 2025
  1. C. Li, Y. Zhang, N. Zhu, H. N. Emady, Experimental investigation of wet pharmaceutical granulation using in-situ synchrotron X-ray imaging. Powder Technol. 378, 65-75 (2021). https://doi.org/10.1016/j.powtec.2020.09.063. [Google Scholar]
  2. P. Thapa, D. H. Choi, M. S. Kim, Effects of granulation process variables on the physical properties of dosage forms by combination of experimental design and principal component analysis. Asian J. Pharm. Sci. 14, 287304 (2019). https://doi.org/10.1016/j.ajps.2018.08.006. [Google Scholar]
  3. M. Matsushita, S. Ohsaki, S. Nara, H. Nakamura, Effect of fill level in continuous twin-screw granulator: A combined experimental and simulation study. Adv. Powder Technol. 33, 103822 (2022). https://doi.org/10.1016/j.apt.2022.103822. [Google Scholar]
  4. S. V. Lute, R. M. Dhenge, Twin Screw Granulation: An Investigation of the Effect of Barrel Fill Level. Pharmaceutics. 10, 67 (2018). https://doi.org/10.3390/pharmaceutics10020067. [Google Scholar]
  5. M. Verstraeten, D. Van Hauwermeiren, K. Lee, N. Turnbull, D. Wilsdon, M. am Ende, P. Doshi, C. Vervaet, D. Brouckaert, I. Nopens, and T. D. Beer, In-depth experimental analysis of pharmaceutical twin-screw wet granulation in view of detailed process understanding. Int. J. Pharm. 529, 678-693 (2017). https://doi.org/10.1016/j.ijpharm.2017.07.045. [Google Scholar]
  6. M. A. Emin and H. P. Schuchmann, Analysis of the dispersive mixing efficiency in a twin-screw extrusion processing of starch based matrix. Food Eng. 115, 132-143 (2013). https://doi.org/10.1016/j.jfoodeng.2012.10.008. [Google Scholar]
  7. T. Ishikawa, T. Amano, Funatsu, Flow patterns and mixing mechanisms in the screw mixing element of a co-rotating twinscrew extruder. Polym. Eng. Sci. 42, 925-939 (2002). https://doi.org/10.1002/pen.11002. [Google Scholar]
  8. C. Zheng, L. Zhang, N. Govender, DEM analysis of residence time distribution during twin screw granulation. Powder Technol. 377, 924938 (2021). https://doi.org/10.1016/j.powtec.2020.09.049. [Google Scholar]
  9. M. Combarros, H. J. Feise, H. Zetzener, Segregation of particulate solids: Experiments and DEM simulations. Particuology. 12, 25-32 (2014). https://doi.org/10.1016/j.partic.2013.04.005. [Google Scholar]
  10. L. Wu, J. Qian, L. Xie, DEM modeling direct shearing behavior of sand considering anti-rotation of particle. Sci. Rep. 13, 8941 (2023). https://doi.org/10.1038/s41598-023-34933-y. [Google Scholar]
  11. P. A. Cundall and O. D. L. Strack, A discrete numerical model for granular assemblies. Géotechnique. 29, 47-65 (1979). https://doi.org/10.1680/geot.1979.29.1.47. [Google Scholar]
  12. Y. Tsuji, T. Kawaguchi, Discrete particle simulation of two-dimensional fluidized bed. Powder Technol. 77, 79-87 (1993). https://doi.org/10.1016/0032-5910(93)85010-7. [Google Scholar]
  13. T. Mikami, H. Kamiya, Numerical simulation of cohesive powder behavior in a fluidized bed. Chem. Eng. Sci. 53, 1927-1940 (1998). https://doi.org/10.1016/S0009-2509(97)00325-4. [Google Scholar]
  14. G. Lian, C. Thornton, A Theoretical Study of the Liquid Bridge Forces between Two Rigid Spherical Bodies. J. Colloid Interface Sci. 161, 138-147 (1993). https://doi.org/10.1006/jcis.1993.1452. [Google Scholar]
  15. B. Remy, J. G. Khinast, Wet granular flows in a bladed mixer: Experiments and simulations of monodisperse spheres. AlChE J. 58, 3354-3369 (2012). https://doi.org/10.1002/aic.13743. [Google Scholar]
  16. E. W. Chuan Lim, R. B. Hee Tan, Mixing behaviors of wet granular materials in gas fluidized bed systems. AlChE J. 59, 4058-4067 (2013). https://doi.org/10.1002/aic.14177. [Google Scholar]
  17. Y. Wang, K. Iyer, A. Esteghamatian, J. E. Meyer, P. Doshi, and E. Wee Chuan Lim, (Manuscript in peer review). [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.