Open Access
Issue
EPJ Web Conf.
Volume 348, 2026
3rd International Conference on Innovations in Molecular Structure & Instrumental Approaches (ICMSI 2026)
Article Number 02005
Number of page(s) 16
Section Chemistry
DOI https://doi.org/10.1051/epjconf/202634802005
Published online 21 January 2026
  1. Shewiyo DH, Kaale E, Risha PG, Dejaegher B, Smeyers-Verbeke J, Vander Heyden Y. HPTLC methods to assay active ingredients in pharmaceutical formulations: A review of the method development and validation steps. J Pharm Biomed Anal. 2012; 66:11–2. [Google Scholar]
  2. Sonia K, Bhavya Shree B, Lakshmi KS. HPTLC method development and validation: An overview. J Pharm Sci Res. 2017;9(5):652–7. [Google Scholar]
  3. Prajapati P, Kapupara P, Vekariya H. Simultaneous analysis of remogliflozin etabonate and vildagliptin in tablets by HPTLC: Method development and validation. Res J Pharm Technol. 2024;17(12):5697–5701. [Google Scholar]
  4. Metformin [Internet]. Available from: https://go.drugbank.com/drugs/DB00331 [Google Scholar]
  5. Teneligliptin [Internet]. Available from: https://go.drugbank.com/drugs/DB11950 [Google Scholar]
  6. Pioglitazone [Internet]. Available from: https://go.drugbank.com/drugs/DB01132 [Google Scholar]
  7. Jamwal N. Systematic review on medicaments used in management of diabetes mellitus. Int J Pharm Pharm Sci. 2020;12(8):1–5. [Google Scholar]
  8. International Conference on Harmonization (ICH). Validation of Analytical Procedures: Text and Methodology Q2(R1). [Google Scholar]
  9. Pandya S, Vekaria HJ. Analytical methods for estimating metformin hydrochloride, pioglitazone, and teneligliptin in diabetes management: A comprehensive review. J Chromatogr Sci. 2025;63(3):1–9. [Google Scholar]
  10. Vekaria H, Limbasiya V, Patel P. Development and validation of RP-HPLC method for simultaneous estimation of Montelukast Sodium and Fexofenadine hydrochloride in combined dosage form. J Pharm Res. 2013;6:134–9. [Google Scholar]
  11. Patel BN, Vekaria HJ. Forced degradation studies and development of RP-HPLC method for related substances of Tenofovir alafenamide in tablet dosage form. Anal Chem Lett. 2023;13(3):321–36. [Google Scholar]
  12. Mishra K, Soni H, Nayak G, Patel SS, Singhai AK. Method Development and Validation of Metformin Hydrochloride in Tablet Dosage Form. E-J Chem. 2011;8(3):1309–13. [Google Scholar]
  13. Arayne MS, Sultana N, Zuberi MH. Development and Validation of RP-HPLC Method for the Analysis of Metformin. Pak J Pharm Sci. 2006;19(3):231–5. [Google Scholar]
  14. Sen AK, Hinsu DN, Sen DB, Zanwar AS, Maheshwari RA, Chandrakar VR, et al. Analytical method development and validation for simultaneous estimation of Teneligliptin hydrobromide hydrate and Metformin hydrochloride from its pharmaceutical dosage form by three different UV spectrophotometric methods. J Appl Pharm Sci. 2016;6(09):157–65. [Google Scholar]
  15. Vetapalem R, Yejella RP, Atmakuri LR. Development and validation of a stability indicating RP-HPLC method for simultaneous estimation of teneligliptin and metformin. Turk J Pharm Sci. 2020;17(2):141–8. [Google Scholar]
  16. Gadapa N, Tripathi UM. RP-HPLC analytical method development and validation for simultaneous estimation of three drugs: glimepiride, pioglitazone, and metformin and its pharmaceutical dosage forms. J Chem. 2013;2013:1–8. [Google Scholar]
  17. Singh D, Dwivedi SC, Kushnoor A. Development and validation of a HPTLC method for estimation of pioglitazone in bulk and tablet dosage form. J Pharm Res. 2011;4(11):3919–21. [Google Scholar]
  18. Dubey S, Kashyap P, Pandey A, Thakur D. A validated method development for estimation of pioglitazone by first-order derivative spectroscopy. Int J PharmTech Res. 2013;5(4):1451–5. [Google Scholar]
  19. Dharmamoorthy G, Nandini Y, Anupama M, Sai Nandhini M, Jhansi Grace Susmitha K, Kesava Reddy Y. Development and validation of stability indicating HPTLC method for the simultaneous estimation of metformin hydrochloride and pioglitazone in pharmaceutical dosage form. YMER. 2022;21(8):612–26. [Google Scholar]
  20. Sengupta P, Bhaumik U, Ghosh A, Sarkar AK, Chatterjee B, Bose A, et al. LC-MS-MS development and validation for simultaneous quantitation of metformin, glimepiride, and pioglitazone in human plasma and its application to a bioequivalence study. J Chromatogr B. 2009;69:1243–50. [Google Scholar]
  21. Kusuma Kumari G, Krishnamurthy PT, Ammu RVVV, Vishwanath K, Narenderan ST, Babu B, et al. Development and validation of a sensitive LC-MS/MS method for pioglitazone: application towards pharmacokinetic and tissue distribution study in rats. RSC Adv. 2021;11:11437–43. [Google Scholar]
  22. Modi DK, Patel BH. Rapid and sensitive simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in tablet formulation by HPTLC method. J Liq Chromatogr Relat Technol. 2013;36(5):618–27. [Google Scholar]
  23. Patel BD, Vekaria HJ. Central Composite Design Expert-Supported RP-HPLC Optimization and Quantitative Evaluation of Efonidipine Hydrochloride Ethanolate and Chlorthalidone in Tablet. J Chromatogr Sci. 2024;62(6):585–92. [Google Scholar]
  24. Patel BN, Vekaria HJ. A stability indicating reverse phase high performance liquid chromatography method for related substances of Sofosbuvir in tablet dosage form. Int J Pharm Sci Drug Res. 2023;15(05):547–55. [Google Scholar]

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