Issue |
EPJ Web Conf.
Volume 287, 2023
EOS Annual Meeting (EOSAM 2023)
|
|
---|---|---|
Article Number | 03005 | |
Number of page(s) | 2 | |
Section | Topical Meeting (TOM) 3- Biophotonics | |
DOI | https://doi.org/10.1051/epjconf/202328703005 | |
Published online | 18 October 2023 |
https://doi.org/10.1051/epjconf/202328703005
Fast Adaptive Optics in optically sectioned fluorescence microscopes for functional neuroimaging
1 Imagine Optic, 91400 Orsay, France
2 Institut des Sciences Moléculaires d’Orsay (ISMO), 91400 Orsay, France
3 Ecole Normale Supérieure – Institut de Biologie (ENS-IBENS), 75005 Paris, France
* Corresponding author: fharms@imagine-optic.com
Published online: 18 October 2023
We demonstrate how a novel approach for closed-loop Adaptive Optics (AO) specifically adapted to microscopy enables straightforward integration in Light-Sheet and Multiphoton microscopes, as well as fast aberration correction. We present corresponding experimental setups as well as first demonstrations of the benefits of the correction of sample-induced aberrations in zebrafish and mouse brain tissue, with the ultimate goal to enable high-speed, high-sensitivity functional imaging at large depths.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.