Issue |
EPJ Web Conf.
Volume 287, 2023
EOS Annual Meeting (EOSAM 2023)
|
|
---|---|---|
Article Number | 03010 | |
Number of page(s) | 2 | |
Section | Topical Meeting (TOM) 3- Biophotonics | |
DOI | https://doi.org/10.1051/epjconf/202328703010 | |
Published online | 18 October 2023 |
https://doi.org/10.1051/epjconf/202328703010
Terahertz ATR sheds light on real-time exchange kinetics occurring through plasma membrane during photodynamic therapy
1 Laboratory for Optics and Biosciences, Ecole polytechnique, CNRS, INSERM, IP Paris, Palaiseau, France
2 Laboratoire des IMRCP, Université de Toulouse, CNRS UMR 5623, 31062 Toulouse, France
3 Centre de Microscopie Electronique Appliquée à la Biologie, Université de Toulouse, 31062 Toulouse, France
* Corresponding author: Guilhem.Gallot@polytechnique.edu
Published online: 18 October 2023
THz ATR spectroscopy provides, in a single measurement, the relative number of defects per membrane surface created by oxidative stress generated during photodynamic therapy (PDT), offering early, sensitive real-time information. THz spectroscopy is therefore a complementary technique to established (biological) assays and can be applied to any topic requiring the real-time examination of short-term plasma membrane permeabilization.
© The Authors, published by EDP Sciences, 2023
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